SPAIN host Portugal on Thursday night in a mouth-watering clash to get their latest Nations League campaigns underway.
The latest edition of the Iberian Derby will take place in Seville, with Switzerland and Czech Republic the other two sides in Group A2.
Spain go into the match as favourites with bookies Paddy Power and Betfair offering odds of 11/10 for a Spanish victory.
Luis Enrique's side go into the new campaign as runners-up from last year's competition.
La Roja won their group containing Germany, Switzerland and Ukraine and defeated newly-crowned European champions Italy in Milan in the semi-final.
However, Luis Enrique's men were defeated 2-1 by France in the final, having been 1-0 up with 25 minutes to go.
Portugal, who won the first edition of the competition back in 2019, are being priced as 13/5 underdogs for Thursday's game.
The Selecao couldn't repeat the feat last year, finishing second in their group that contained France, Croatia and Sweden.
A draw is priced at 23/10 by Sky Bet.
According to Sky Bet, Cristiano Ronaldo is most likely to score the first goal of the game, with 9/2 odds for the Manchester United forward to bag first.
However, Betfair and Paddy Power both price the Spaniard Raul de Tomas with the shortest odds, with the Espanyol striker at 7/2 to get the first goal.
The last four meetings between the two sides have all ended in draws, most notably a 3-3 draw in Russia in the 2018 World Cup, as well as the semi-finals of Euro 2012 in Ukraine, which Spain won on penalties.
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