Mum-of-22 Sue Radford has said that 'life can be hard' as she enjoyed a family holiday amid a rumoured fallout with her pregnant daughter Millie.

Sue, who is mum to Britain’s biggest brood, which she shares with husband Noel, reflected on her difficulties as the huge family enjoyed their 18th holiday in 20 months.

The mum took to Instagram to share a snap of her family splashing around in a swimming pool as they enjoyed a trip to a villa in sunny Miami.

The 48-year-old penned: "Just love watching them having so much fun. Sometimes life is hard but these moments are what we live for."

Her daughter Millie was noticeably absent from the trip after making a dig at her famous mum after Sue and the rest of the family went on holiday to Orlando without her and her children.

The 22-year-old, who is pregnant with her third child, screenshotted a video of the trip on Instagram before hitting out, saying: "Cute? But you've made money from all your grandchildren but choose your favourites."

Millie then went on to accuse her parents of snubbing her two children, Ophelia and Chester, despite them featuring in the 22 Kids and Counting show.

As she prepares to give birth for the third time, the TV star later shared a cryptic post about hard times on Instagram.

While Millie didn’t confirm who her post was aimed at, she encouraged her followers to keep the people in their life who 'show up during hard times'.

The emotional post also said to pick those who 'reciprocate effort', 'are willing to communicate', and 'celebrate your good news'.

The heavily pregnant Radford family sibling recently revealed her own good news after sharing with her fans that she’s expecting a little girl.

Despite the rift between Sue and her daughter, the mum-of -22 has continued to take her giant family on multiple vacations.

In the past two months, Britain’s biggest brood have enjoyed domestic trips to Cornwall and the Lake District, as well as jetting off to New York, France, the Maldives and the Laplands.

And the adventure – seeking family have also enjoyed trips to the likes of Legoland and Alton Towers, as well as three separate trips to Disneyland

The Radfords have documented their most recent trip to the sun-soaked state of Florida on their YouTube channel, revealing that it took 15 suitcases to get the family overseas.

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