The Denver Broncos (2-5) visit the Indianapolis Colts (4-2) at Lucas Oil Stadium Sunday of Week 4. Kickoff is scheduled for 1 p.m. ET. We analyze the Broncos-Colts odds, lines and spread, while providing NFL betting tips on the best action around this matchup.

The Colts have won two straight games. Meanwhile, the Broncos have lost three of their last five contests.

Broncos at Colts: Week 8 preview, betting trends, and notes


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  • The Colts are coming off a 30-23 Week 7 home win over the Houston Texans. The Broncos lost 30-6 at home to the Kansas City Chiefs.
  • Broncos QB Joe Flacco has one or fewer pass TD in eight of his last nine games (0 pass TD four times).
  • Colts WR T.Y. Hilton has not had a 100-yard receiving game since Week 16, 2018.
  • Indianapolis has outscored its opponents 143-138. Meanwhile, Denver has been outscored 136-112. Only two teams in the AFC have a worse point-per-game average offensively than the Broncos.
  • The Colts are 4-1-1 against the spread, covering by an average of 2.8 points. The Broncos are 3-4 ATS and have fallen an average of 1.9 points short of the cover.
  • Denver is 1-2 ATS as the road team this season falling short of the number by 1.3 points per contest. Indianapolis is 2-1 as the home team ATS falling short of the projection by -1.7 points per game.
  • Indy is 4-2 against the over/under, missing the projection by an average of 0.5 points. Denver is 2-5 and falling 7.3 points short of the projected total on average.
  • Colts QB Jacoby Brissett has completed 65% of his 206 passing attempts for 1,388 yards with 14 touchdowns and three interceptions as the starter.
  • Flacco is completing 65.7% of his passes with 1,648 yards, six touchdowns and five interceptions.
  • Denver ranks third defensively in passing yards allowed at 195.2 yards per game and 4th overall at 302.57 yards per game.
  • Indianapolis ranks in the bottom half of the league in total yards and points allowed per game.
  • The Colts have won four of their last five games while the Broncos have lost three of their previous five.

Broncos at Colts: Key injuries

Colts WR T.Y. Hilton (rest) should play Sunday. Carl Davis and Pierre Desir are questionable with hamstring injuries.

Broncos CB Bryce Callahan and S Will Parks did not practice Thursday, but were not ruled out.

Broncos at Colts: Odds, betting lines and prediction

NFL odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 5:45 p.m. ET.

Prediction

Colts 27, Broncos 13

Moneyline ( ?)

The Colts get the edge at home against a below-average Broncos team. The -250 (up from -225) odds for the Colts to win outright, however, is far too chalky with a $10 wager returning a profit of just $4.00. Bet the spread.

Against the Spread ( ?)

The -5.5 is not too big of a number for the Colts. Get the Colts at -5.5 with -115 (previously even money) odds returning a profit of $8.70 on a $10 wager as long as they win by six points or more.

Over/Under (?)

Lean only slightly to the UNDER 43.5 (-115), as the Broncos are retooling on offense, which has already struggled plenty this season.

Chris’s NFL betting record: 27-18

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