Nick Cannon is mourning an unimaginable loss. The 41-year-old TV personality announced Tuesday on The Nick Cannon Show that his youngest son, 5-month-old Zen, died of brain cancer.

Cannon and Alyssa Scott welcomed Zen back in June, making him Cannon's seventh child. On his show, the father of seven tearfully shared how he and his family discovered Zen was battling Hydrocephalus, a form of brain cancer.

According to the Mayo Clinic, Hydrocephalus "is the buildup of fluid in the cavities (ventricles) deep within the brain. The excess fluid increases the size of the ventricles and puts pressure on the brain."

"I always noticed he had a cough and so I wanted to check it out," he said. "He had this interesting breathing and by the time he was two months I noticed he had this nice sized head too — a Cannon head. We didn’t think anything of it. But I wanted to take him to the doctor for his sinus and breathing. We thought it would be routine."

A MESSAGE FROM NICK. @NickCannon WATCH NOW – https://t.co/hpxKJH6EEspic.twitter.com/mzDiTSCA3L

— Nick Cannon (@NickCannonShow) December 7, 2021

The family quickly discovered that it was not a routine visit and that Zen had fluid building in his head and it was a malignant tumor. The baby had brain surgery and a shunt to drain the fluid.

Cannon shared that things took a turn for the worse at Thanksgiving.

"This weekend I made an effort to spend the most quality time with Zen. We woke up on Sunday and went to the ocean with him and Alyssa and then I had to fly back to New York for the show," he shared, breaking down in tears. "I got a call on my way to the airport to head back to Zen."

Cannon then tearfully shared that he held his son for the last time this weekend. "You can't heal until you feel," he told the audience, adding that he's at work so soon after because this is all he knows, calling the episode a "celebration of life" for Zen.

Cannon is taking some time off. A source tells ET that his show "was scheduled to have two show tapings on Monday, including a live show. Those were both unexpectedly canceled on Sunday and a pre-taped episode was aired on Monday instead."

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